As well as staying open to look after the children of key-workers, and keeping in touch with the rest of their pupils through on-line classes and learning, schools have added another subject to the daily curriculum - making PPE.
Since they were closed on 20 March schools throughout the city have not only been looking after the children of key-workers, they have also been playing a vital part in helping keep key-worker parents safe by setting up mini production hubs in school to make PPE for them.
Those schools without the equipment to make PPE have also helped the city-wide effort by donating all of their own PPE supplies such as goggles used in science labs to local hospitals and care homes.
One of the first schools to get involved in donating and producing PPE was Parrs Wood High School. On the first day of the national lockdown their lead science technician organised for all of the school's unopened PPE - goggles, aprons and masks - to be sent to the Manchester Royal Infirmary after seeing they needed some on Twitter.
Since then the school's technology department - helped by key worker children - has also made literally hundreds of visors for local care homes, medical practices, and the Intensive Care Unit at Wythenshawe Hospital. They have also made wash bags for NHS staff to put their uniforms in to wash them, and comfort clips for protective face masks.
Headteacher Mark McElwee said: "It's impossible to properly do justice to what our NHS and carers are doing for us at the moment - they are being so incredibly brave and are genuinely real heroes. We wanted to do whatever we could to help by donating and making extra PPE, and as a token of our appreciation, we also sent some care packages through to staff in our local hospitals to let them know just how grateful we are."
Staff at Manchester Enterprise Academy also sprang into action early on to help produce vital PPE after getting a phone call from a retired secondary headteacher, who is the mother of a staff member at Wythenshawe Hospital.
After being sent a link to an on-line specification, they teamed their expertise and set to work with their laser cutter to produce an initial batch of 50 protective visors for staff at the hospital to wear in the battle against COVID-19.
Since then the school's Art and Design Team have stepped up production, receiving orders for 450 more visors from a number of community health organisations.
Maggie McManus, one of the staff members involved in making PPE, said: "At this time of year we would normally be incredibly busy preparing students for exams in a building full of staff and children. As teachers, we feel a bit lost without the hustle and bustle of school life, and it has been good to be involved in a project that is making a real difference during such a strange time."
Other schools that have been putting their skills and equipment to good use include Chorlton High School who have donated goggles to local hospitals, and Trinity High School whose engineering department have been busy making visors for a number of different hospitals.
Councillor Garry Bridges, Executive Member for Children and Schools, Manchester City Council, said: "I could not be prouder of the way our schools have responded to the current situation.
"Not only are their teachers delivering lessons and learning to thousands of home-school classrooms across the city, and staying open to provide care for the children of key-workers, our schools are also making and delivering vital and much-needed PPE to local hospitals, health centres, and care homes.
"They got straight down to business in the first week of the lockdown and haven't stopped since. Their positivity in the face of such adversity has been amazing to see and there are life lessons in this for all of us - thank you!"